Test ID SYPHT Syphilis Total Antibody with Reflex, Serum
Specimen Required
Collection Container/Tube: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Secondary ID
603264Useful For
Aiding in the diagnosis of recent or past Treponema pallidum infection
Routine prenatal screening
This test is not offered as a screening or confirmatory test for blood donor specimens.
This test is not useful for diagnosis of congenital syphilis.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| RTPPA | Syphilis Ab, TP-PA, S | Yes, (Order TPPA) | No |
| RRPRQ | RPR Titer, S | No | No |
| SYPNB | Syphilis Total Ab Bill Only 1 | No, (Bill Only) | No |
| RRPRS | RPR Screen w/ Reflex to Titer, S | No | No |
Testing Algorithm
If the syphilis total antibody result is nonreactive, billing will be captured under SYPNB.
If the syphilis total antibody result is reactive or equivocal, then the rapid plasma reagin (RPR) screen will be performed, and billing will be captured under SYPNB.
If the RPR screen is positive, then the RPR titer will be performed at an additional charge.
If the RPR screen is negative, then syphilis antibody Treponema pallidum particle agglutination testing will be performed at an additional charge.
Method Name
SYPHT: Multiplex Flow Immunoassay
RRPRQ, RRPRS: Flocculation/Agglutination
RTPPA: Particle Agglutination
Reporting Name
Syphilis Total Ab w/ Reflex, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat-inactivated specimen | Reject |
Reference Values
SYPHILIS TOTAL ANTIBODY
Nonreactive
RAPID PLASMA REAGIN SCREEN
Negative
RAPID PLASMA REAGIN TITER
Negative
SYPHILIS ANTIBODY, Treponema pallidum-PARTICLE AGGLUTINATION
Negative
Reference values apply to all ages
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysPerforming Laboratory
Mayo Clinic Laboratories in Arizona
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86780
86780-Syphilis Antibody by TP-PA (if appropriate)
86593-Rapid Plasma Reagin Titer (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SYPHT | Syphilis Total Ab w/ Reflex, S | 47236-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SYPHT | Syphilis Total Ab w/ Reflex, S | 47236-5 |